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Drug ReportsHeparin sodium
Heparin sodium
Calciparine, Defencath, Embolex, Heparin (heparin sodium) is an oligosaccharide pharmaceutical. Heparin sodium was first approved as Calciparine on 1982-01-01. It is used to treat cerebral infarction, coronary thrombosis, myocardial infarction, postoperative complications, and pulmonary embolism amongst others in the USA. The pharmaceutical is active against antithrombin-III.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
nervous system diseasesD009422
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
defencathNew Drug Application2024-12-23
heparinunapproved drug other2012-08-09
heparin sodiumunapproved drug other2014-12-24
heparin sodiumANDA2025-01-08
heparin sodium and dextroseNew Drug Application2024-11-30
heparin sodium and sodium chlorideNew Drug Application2019-04-19
heparin sodium in dextroseNew Drug Application2023-07-31
heparin sodium in sodium chlorideNew Drug Application2024-01-27
iceking freckle removing whitening facial cleanser iceking freckle removing whitening masque iceking refresh armpit iceking repellent mosquito icek...Export only2018-07-23
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration
Code
HEPARIN SODIUM / TAUROLIDINE, DEFENCATH, CORMEDIX
2033-11-15GAIN
2028-11-15NCE
Patent Expiration
Patent
Expires
Flag
FDA Information
Heparin Sodium / Taurolidine, Defencath, Cormedix
117381202042-04-15DS, DP
76961822025-05-16DS, DPU-3774
85413932024-11-02DS, DPU-3774
93390362024-11-02DS, DP
ATC Codes
B: Blood and blood forming organ drugs
B01: Antithrombotic agents
B01A: Antithrombotic agents
B01AB: Heparin group antithrombotic drugs
B01AB01: Heparin
B01AB51: Heparin, combinations
B01AC: Platelet aggregation inhibitors excl. heparin
B01AC30: Platelet aggregation inhibitor combinations excl. heparin
C: Cardiovascular system drugs
C05: Vasoprotectives
C05B: Antivaricose therapy drugs
C05BA: Heparins or heparinoids for topical use
C05BA03: Heparin
C05BA53: Heparin, combinations
S: Sensory organ drugs
S01: Ophthalmologicals
S01X: Other ophthalmologicals in atc
S01XA: Other ophthalmologicals in atc
S01XA14: Heparin
HCPCS
Code
Description
J1642
Injection, heparin sodium, (heparin lock flush), per 10 units
J1643
Injection, heparin sodium (pfizer), not therapeutically equivalent to j1644, per 1000 units
J1644
Injection, heparin sodium, per 1000 units
Clinical
No data
Drug
General
Drug common nameHeparin sodium
INNheparin sodium
Description
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that increases the activity of antithrombin. It is used in the treatment of heart attacks and unstable angina. It can be given intravenously or by injection under the skin. Its anticoagulant properties make it useful to prevent blood clotting in blood specimen test tubes and kidney dialysis machines.
Classification
Oligosaccharide
Drug classheparin derivatives and low molecular weight (or depolymerized) heparins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID9005-49-6
RxCUI5224
ChEMBL IDCHEMBL1201657
ChEBI ID
PubChem CID22833565
DrugBankDB01109
UNII IDZZ45AB24CA (ChemIDplus, GSRS)
Target
Agency Approved
SERPINC1
SERPINC1
Organism
Homo sapiens
Gene name
SERPINC1
Gene synonyms
AT3
NCBI Gene ID
Protein name
antithrombin-III
Protein synonyms
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, Serpin C1, serpin peptidase inhibitor clade C member 1, serpin peptidase inhibitor, clade C (antithrombin), member 1
Uniprot ID
Mouse ortholog
Serpinc1 (11905)
antithrombin-III (P32261)
Alternate
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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